Thursday, July 29, 2021

Converting a file with .json format to a file with .csv format using PowrShell

  The easiest way to do this is to use Windows Powershell as described here. It is enough if you convert .json to .csv. File format .cssv can be opened with EXCEL and saved.

This is the .json file:

============

{

   "Name": "James Bond",

   "Age": "35",

   "Profession": "Professional Killer",

   "Location": "London, UK"

}

===================

This file, JamesBond.json  is saved on my desktop.

Let us say that is the code you need to convert to from .json to .csv format

Create the above text in Notepad and save it with the extension .json (default is .txt for Notepad)


Open the Windows PowerShell ISE




Type in the following code (try to see what else you can convert from and convert to in the above images):

Get-Content C:\Users\TestUser\Desktop\JamesBond.json | ConvertFrom-Json|ConvertTo-Csv

Run the code in the Windows PowerShell ISE

You will see this result:

==========================

"Name","Age","Profession","Location"

"James Bond","35","Professional Killer","London, UK"

---------------------------------

You get the answer as shown. 

This is in CSV format and this can be opened with EXCEL.


This can be saved as .xlsx or various other formats.






Sunday, July 25, 2021

Thursday, July 22, 2021

Start playing games on ZOOM

 A new game for the videoconferencing app ZOOM

Now you can not only collaborate but you can also play games. Of course, collaboratively I hope. More and more people jumping on to Games (I heard Netflix is going the games way). Is it healthy? 

How do we find time to play games? It does not bode well for corporate culture with so many games around. Anyway, it is game time, and if you have Zoom on your device try it out.

https://www.cnet.com/tech/services-and-software/zoom-added-games-to-play-during-meetings-heres-how-to-do-it/?ftag=CAD3c77551&bhid=25677796175134485681691771088700&mid=13446301&cid=643639471

These are the steps to play games on ZOOM quoted from the above site:

1. Log in to Zoom. 

2. Search for Live Game Poker Night or Heads Up in the Zoom App Marketplace. Install the game. 

3. Start a Zoom meeting as normal.

4. Click the Zoom Apps tab at the bottom of the meeting window to launch the game. 

5. Once the host has configured any game options and set up the game, players will be taken to the poker room to play. 

Quick and easy online compiler

 Look no further for easy coding.

myCompiler is a quick and easy online compiler that has an easy interface. It does not come with bells and whistles but it does well what it does. It supports many languages. Give it a try.

Here is an example using SQL:

https://hodentekhelp.blogspot.com/2021/07/is-there-online-compiler-for-multiple.html



Wednesday, July 21, 2021

I thought Hydrogen was colorless

 Yes, it is colorless. This is what elementary chemistry tells you. But people may be wondering why they are adding a color attribute to hydrogen.

The color attribute of hydrogen comes about by the way it is produced on an industrial scale. There are three colors presently:

Grey hydrogen:

Basically from fossil fuels such as coal or natural gas.

https://www.coalage.com/features/hydrogen-from-coal/#:~:text=H%202%20produced%20by%20steam%20methane%20reforming%20%28SMR%29,hydrogen%20that%20includes%20carbon%20abatement%2C%20such%20as%20CCUS.

https://tinyurl.com/yey9fegt


By far most of the hydrogen presently produced/used is grey hydrogen. If electricity is produced from fossil fuels the advantage of EV is not so great.

Green hydrogen:

Hydrogen from Electrolysis of water.

This is completely free of carbon in its production.

http://www.chem.gla.ac.uk/cronin/media/papers/Chisholm-Chapter_16_2016.pdf#:~:text=The%20production%20of%20hydrogen%20from%20water%20via%20electrolysis,has%20two%20main%20applications%20as%20an%20energy%20vector.

or

https://tinyurl.com/4y6hektf

Blue hydrogen:

It is similar to Grey hydrogen but the carbon in the process is captured and stored (so-called carbon neutral).

https://www.msn.com/en-us/news/technology/blue-gas-could-become-a-tesla-killer/ar-BB1dOsgr#:~:text=So-called%20%27blue%27%20hydrogen%20is%20the%20name%20given%20to,water%20are%20converted%20into%20hydrogen%20and%20carbon%20monoxide.

https://tinyurl.com/e5k7zrxe

Saturday, July 10, 2021

How are COVID-19 (Wuhan Virus) variants classified?

WHO has classified them as Variants of Interest (VOI) and Variants of Concern (VOC).
Here is a list from the WHO site mentioned in this post.

Variants of Interest:




Variants of Concern:



Mayo Clinic seems to think that the vaccines developed for COVD-19 are not so efficient against the mutations observed in the variants. 

Hence there is movement to create booster shots which translates to more business for the vaccine makers. Are we seeing the light at the end of the tunnel, or the tunnel is bifurcating in all directions?

Variants causing concern in the US (https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/covid-variant/faq-20505779) are:

"Alpha. (B.1.1.7). This COVID-19 variant appears to spread more easily and might have an increased risk of hospitalization and death.

Beta (B.1.351). This variant appears to spread more easily. It also reduces the effectiveness of some monoclonal antibody medications and the antibodies generated by a previous COVID-19 infection or COVID-19 vaccine.

Gamma (P.1). This variant reduces the effectiveness of some monoclonal antibody medications and the antibodies generated by a previous COVID-19 infection or a COVID-19 vaccine.

Epsilon (B.1.427). This variant appears to spread more easily. It reduces the effectiveness of antibodies generated by a previous COVID-19 infection or COVID-19 vaccine.

Epsilon (B.1.429). This variant appears to spread more easily. It reduces the effectiveness of antibodies generated by a previous COVID-19 infection or COVID-19 vaccine.

Delta (B.1.617.2). This variant appears to spread more easily. It might reduce the effectiveness of some monoclonal antibody treatments and the antibodies generated by a COVID-19 vaccine.
"

Colombian Variant:
The B.1.621 variant has been reported in 26 different countries and territories since it was first recorded by the World Health Organization, including the U.S.











Wednesday, July 07, 2021

Breaking news: COVAXIN Reports on phase 3 trial

 COVAXIN: Phase 3 Interim Report

On 3rd July 2021 Bharath Biotech based in India's Genome Valley announced their Phase 3 interim results of Covid vaccine BBV152(COVAXIN). The pdf link describes some details. 

The bulleted highlights are as follows:

"

  •  Data from 25,800 participants, received vaccine or placebo in a 1:1 ratio showed that

the vaccine candidate was well tolerated.

  •   COVAXIN® demonstrated 81% interim efficacy in preventing COVID-19 in those without

prior infection after the second dose.

  •   Clinical trial to continue through to final analysis at 130 confirmed cases in order to

gather further data and evaluate the efficacy of COVAXIN in additional secondary

study endpoints.

"

One of the key points to note;

"The inclusion of the Algel-IMDG adjuvant enhances T-cell immune responses to COVID-19, leading to long-term protection"

Vaccine distribution status:

4 billion doses distributed worldwide so far.

More here on Bharath Biotech:

http://www.bharatbiotech.com/

https://www.bharatbiotech.com/images/press/covaxin-phase3-efficacy-results.pdf

What is an adjuvant?

In immunology, an adjuvant is a substance that increases or modulates the immune response to a vaccine. The word "adjuvant" comes from the Latin word adiuvare, meaning to help or aid. Wikipedia


More on NIH related information in quotes:

"The adjuvant used in COVAXIN, Alhydroxiquim-II, was discovered and tested in the laboratory by the biotech company ViroVax LLC of Lawrence, Kansas with support exclusively from the NIAID Adjuvant Development Program. The adjuvant comprises a small molecule attached in a unique way to Alhydrogel, a substance frequently called alum that is the most commonly used adjuvant in vaccines for people. Alhydroxiquim-II travels to lymph nodes, where the small molecule detaches from alum and activates two cellular receptors. These receptors, TLR7 and TLR8, play a vital role in the immune response to viruses. Alhydroxiquim-II is the first adjuvant in an authorized vaccine against an infectious disease to activate TLR7 and TLR8. In addition, the alum in Alhydroxiquim-II stimulates the immune system to search for an invading pathogen."

https://www.financialexpress.com/lifestyle/health/covaxin-to-use-virovaxs-adjuvant-alhydroxiquim-ii-to-boost-immune-response/2098284/

About ViroVax:

"Dr. Sunil David founded (an alumnus of the Indian Institute of Science, Bengaluru)) ViroVax, LLC in 2019 in Lawrence, KS.  ViroVax is a biotechnology company focused on the research and development of vaccines, adjuvants, and therapeutics to protect and treat people from infectious diseases, including Zika, West Nile, Dengue, and SARS-CoV-2.

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