Showing posts with label UK. Show all posts
Showing posts with label UK. Show all posts

Friday, December 31, 2021

Cancer or Cardiovascular diesease?

 Cardiovascular diseases were the most common cause of death among low-income countries (death from cardiovascular was 3X times that from Cancer) that I hail from. It was found to be common even in middle-income countries. However, in high-income countries, Cancer was the winner. It was in fact twice that of people dying from cardiovascular diseases.

Given that cardiovascular diseases are preventable gives us the hope that if only we are intelligent, then it should not be a problem. Knowing a problem is about getting to a 90% solution. 

The stuff that can and should be controlled are:

High blood pressure

Tobacco-related indiscipline

Lack of educational resources

Pollution

It goes without saying that handling all of this is a reasonable way to save lots of lives. If we value science, value data and statistics should we not be proactive?

Cancer is yet another story. Do we need to boost our immunity, hook, or crook? It has been the cause of death in high-income societies (Lata Palaniappan - Stanford University Medical Center). While few of the controllable items were listed for cardiovascular diseases, a similar list for cancer control perhaps does not exist and even if it does it will be extensive and long.

That brings me back to my motivation in writing this. My friend Mr. Narasimhan who lives in the UK wrote to me that he will walk his walk to raise funds for research. This is extremely laudable except that I won't be able to participate as I was getting treated for tendonitis of the foot yesterday.

I wish my friend Narasimhan a happy walk for this cause. 

He is brave doing this in his senior years (80 and 2 summers). We have not met in 50 odd years, but we correspond regularly.

This is an old reference and I bet you can find a recent one in Lancet.

https://www.cnn.com/2019/09/03/health/leading-cause-of-death-cancer-heart-disease-study/index.html


Saturday, July 10, 2021

How are COVID-19 (Wuhan Virus) variants classified?

WHO has classified them as Variants of Interest (VOI) and Variants of Concern (VOC).
Here is a list from the WHO site mentioned in this post.

Variants of Interest:




Variants of Concern:



Mayo Clinic seems to think that the vaccines developed for COVD-19 are not so efficient against the mutations observed in the variants. 

Hence there is movement to create booster shots which translates to more business for the vaccine makers. Are we seeing the light at the end of the tunnel, or the tunnel is bifurcating in all directions?

Variants causing concern in the US (https://www.mayoclinic.org/diseases-conditions/coronavirus/expert-answers/covid-variant/faq-20505779) are:

"Alpha. (B.1.1.7). This COVID-19 variant appears to spread more easily and might have an increased risk of hospitalization and death.

Beta (B.1.351). This variant appears to spread more easily. It also reduces the effectiveness of some monoclonal antibody medications and the antibodies generated by a previous COVID-19 infection or COVID-19 vaccine.

Gamma (P.1). This variant reduces the effectiveness of some monoclonal antibody medications and the antibodies generated by a previous COVID-19 infection or a COVID-19 vaccine.

Epsilon (B.1.427). This variant appears to spread more easily. It reduces the effectiveness of antibodies generated by a previous COVID-19 infection or COVID-19 vaccine.

Epsilon (B.1.429). This variant appears to spread more easily. It reduces the effectiveness of antibodies generated by a previous COVID-19 infection or COVID-19 vaccine.

Delta (B.1.617.2). This variant appears to spread more easily. It might reduce the effectiveness of some monoclonal antibody treatments and the antibodies generated by a COVID-19 vaccine.
"

Colombian Variant:
The B.1.621 variant has been reported in 26 different countries and territories since it was first recorded by the World Health Organization, including the U.S.











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