Getting vaccinated against COVID-19 is not an option. Where do you go next?

 

Source: AstraZeneca site

AZD 7442 is AstraZeneca's long-acting antibody (LAAB) combination (AZD8895 and AZD1061). According to the company, LAAB's mimic natural anitbodies and will be useful in preventing the progression of patients already infected with the virus as well as a prophylactic agent. LAAB's were discovered by Vanderbilt University Medical Center and licensed to AstraZeneca. 

This is especially targeted for people for whom vaccination may not be appropriate. It may also reduce risk for high-risk population. US has funded this program spanning the various phases of study. Phase I was started in August 2020 to assess safety, tolerability and pharmokinetics of this combination in healthy individuals.

It may be noted that, "In a recent Nature publication, the LAABs were shown in pre-clinical experiments to block the binding of the SARS-CoV-2 virus to host cells and protect against infection in cell and animal models of disease."

https://www.nature.com/articles/s41586-020-2548-6

Details of January Phase III trial with 1700 participants are posted details here:

https://www.clinicaltrials.gov/ct2/show/NCT04723394

According to latest news (March 16, 2021), AstraZenca will supply half a million additional doses of anti-body treatement to the US. 

Details (must read) here:

https://www.astrazeneca.com/media-centre/press-releases/2021/us-supply-agreement-for-additional-azd7442-doses.html

Covid-19 Vaccine Developer line up 2020-2021

These are the major companies and the research entities that are hopeful of developing a vaccine. The timeline for delivering a solution is in 2020 - 2021 as of now. Who will make it to the finish line?

The table is copied from Nippon Keizai Shinbun. The last column is my addition for my English audience.

Hopefully, we can get past this universal bug.

Covid-19 Vaccine Hopefuls

Here is a list of vaccine hopefuls to combat the new coronavirus Covid-19.

https://www.benzinga.com/analyst-ratings/analyst-color/20/05/16056298/these-6-coronavirus-vaccine-candidates-are-the-likeliest-to-succeed-says-morgan-sta

According to BGR, a leading online destination for news and commentary focused on the mobile and consumer electronics markets, these are the companies/institutions that are further in bringing in a vaccine for the coronavirus.

According to Fauci, the new coronavirus is not addressed by a vaccine that can provide lifetime immunity and, at best it can provide immunity up to 12 months. It appears to change with time just like the cold virus. He notes with optimism that 100s of millions of doses may be available by 2021.

https://bgr.com/2020/06/03/fauci-vaccine-comments-coronavirus-immunity-length/